As a kind of technology that uses a high energy electron beam to detect objects at nano-scale level, SEM can generate valuable information about various specimens, including shape and size of the particles (morphological information), surface features (topographic information), the elements and compounds (information about the composition), and the arrangement of the objects (crystallographic information). Insect Identification https://iem.creative-biostruct....ure.com/insect-scien

 

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Insect Science Research Using the iEM Platform - Creative Biostucture iEM Platform

Based on specialized equipment, experienced technical staff, and improved methods for the preparation of samples, Creative Biostructure presents SEM for the characterization and analysis of insects.

Lead discovery and optimization play a crucial role to determine the quality of clinical candidates. After this process, a set of compounds can be screened that interact with the target and the confirmed hits have specific activity against the target. Creative Biostructure performs comprehensive lead discovery and optimization solutions including library construction, library screening (in silico, in vitro and in vivo), hit-to-lead optimization and preclinical evaluation, etc. Lead Discovery https://drug-discovery.creativ....e-biostructure.com/l

 

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Lead Discovery and Optimization - Creative Biostructure

Creative Biostructure performs comprehensive lead discovery and optimization solutions including library construction, library screening (in silico, in vitro and in vivo), hit-to-lead optimization and preclinical evaluation, etc.

The analysis of three-dimensional (3D) structure is of great importance for the mechanism of virus infection and the design of antiviral drugs. Although many breakthroughs have been made in structural biology techniques and structure determination methods such as X-ray crystallography, NMR spectroscopy and cryo-electron microscopy (cryo-EM) have been utilized to determine the structure of many biological macromolecules, the process of obtaining the 3D structure of the target protein is still difficult and time-consuming. Facing the continuous spread of the epidemic, we need to accelerate the understanding of the pathogenic mechanism

 

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Protein Homology Modeling for Coronavirus Research - Creative Biostructure

Creative Biostructure can generate structural models of coronavirus/host proteins through calculation methods, which will be a powerful alternative and supplement to the experimental method.

The determination of the secondary and tertiary structure of biomolecules, especially proteins and nucleic acids, is essential for the investigation of biomolecules' functions in their native, biologically active conformation. Circular dichroism (CD) is a powerful tool for understanding the secondary and tertiary structure of proteins, nucleic acids, as well as protein-ligand complexes. It can also characterize the binding interactions of non-immobilized molecules in the solution. Circular Dichroism Spectroscopy https://www.creative-biostruct....ure.com/circular-dic

 

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Circular Dichroism Spectroscopy Service

Creative Biostructure provides circular dichroism spectroscopy services.