Purpose Of ED Medicines  

ED medications are used for relieving the symptoms of erectile dysfunction conditions in men. These are advantageous for men feeling let-down due to frequent episodes of erection failures, even after achieving complete sexual arousal. Kamagra Gold 50 mg is one of the potent ED medications that serve as the most efficient remedial solution for the treatment of erectile dysfunction also known as impotence condition in men. These ED medications are beneficial for dealing with erection failures and must be taken according to the intensity of the condition due to their availability in different strengths. ED medicines deliver utmost sexual satisfaction with their prompt action mechanism which usually starts within 30 to 45 minutes of its consumption.         

Mechanism Of Action Of ED Medicines    

ED medicines are PDE5 inhibitor that helps negate the activity of PDE5 enzymes in the walls of the blood vessels that carry blood to and through the penile shaft. PDE5 enzymes present in the smooth muscle cells in the walls of the blood vessels have a major role in the restriction of the proper flow of blood to the penile. It affects the smooth muscle lining of the penile blood vessels and blocks blood flow. However, ED medicines effectively nullify the action of PDE5 and re-vitalize the blood vessels.    

Further, PDE5 inhibition causes the discharge of a powerful substance known as, Nitric oxide (NO) which causes the generation of the Guanylate cyclase (GC) enzymes which catalyzes the synthesis of cyclic Guanosine Monophosphate (cGMP) enzymes. In this way, the ED medicine metabolizes the cGMP enzymes that relax the muscle blockages by managing the contraction, vasodilation, and regulation of blood in the penile shaft and leads to an erection suitable to be indulging in a long-lasting lovemaking session.

Sexual Stimulation Is Necessary

Its consumption must be combined along with sexual stimulation which ultimately boosts the desire and triggers an erection easily. Since ED medicine is not capable of causing spontaneous erections, one must attain a sexually aroused state for getting a stiffer penile suitable for penetration. Thus, sexual stimulation is necessary for attaining arousal which would initiate a quick response for triggering an erection.   

Avoid Large And Fatty Meals Close To Medicinal Consumption    

Large meals, particularly oily or fatty ones, slow down the rate of absorption and delays the assimilation of the medicine into the bloodstream. It prevents the medicine from exhibiting its intended effects. It is better to consume the medication on an empty stomach which is two hours after the meal. Avoid heavy meals altogether on the day of taking the medicine if possible or you can maintain a long gap between your meal and your medication on that particular day.     

Avoid Combining Smoking Or Alcohol With ED Medicines      

The presence of hazardous chemicals in tobacco or cigarette smoke damages the walls of the penile blood vessels impairs the vascular passages and affects the erection function. It negates the discharge of nitric oxide in the endothelial cells that comprise the inner lining of the blood vessel. Nitric oxide is a powerful substance that relaxes the smooth muscles in the penile, overcomes blockages in the blood vessels by causing vasodilation, and instigates proper blood flow to the penile for promoting an erection. Besides, alcohol slows down the process of absorption of the medicine in the body and it also causes some side effects such as headache, dizziness, vomiting, etc. when combined with the medicine.